#Synergy screen wrap full#
#Synergy screen wrap tv#

We demonstrate our approach using a systematic screen of all possible pairs among 108 cancer drugs applied to melanoma cell lines. We developed an approach suitable for datasets with large number of drugs pairs even if small number of data points are available per drug pair. We describe a statistical and visualization framework for the analysis of large-scale drug combination screens. Furthermore, since the number of pairwise combinations grows with the square of the number of drugs, exploration of large screens necessitates advanced visualization tools. Screening of a sparse number of doses per drug allows to screen large numbers of drug pairs, but complicates statistical assessment of synergy.

#Synergy screen wrap full#

To robustly identify synergistic combinations, high-throughput screens using full dose-response surface are desirable but require an impractical number of data points.

combinations have the potential to improve efficacy while limiting toxicity.

11 Harvard Medical School, Boston, MA, USA.

10 The Center of Cancer Research, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, 02129, USA.

9 Harvard-Ludwig Center for Cancer Research, Boston, MA, USA.

8 Harvard Stem Cell Institute, Cambridge, MA, USA.7 Broad Institute of Harvard and MIT, Cambridge, MA, USA.6 Harvard Medical School, Boston, MA, USA.5 The Center of Cancer Research, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, 02129, USA. 4 Current Address: PatientsLikeMe, 160 Second Street, Cambridge, MA, 02142, USA. 3 Broad Institute of Harvard and MIT, Cambridge, MA, USA. 2 Harvard Medical School, Boston, MA, USA. 1 The Center of Cancer Research, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, 02129, USA.Ssh -t -t bl /home/jim/scripts/restartSynergy. Sudo /usr/sbin/service avahi-daemon restart & # The apparently extraneous '&' below fixes an issue. # need to come up with something to deal with that. # Unfortunately this command returns as soon as it is called regardless, so I Ssh -t -t bl sudo /usr/bin/killall synergyc & #Now we need to kill our synergy server and also stop the client in my laptop. #We are killing pulseaudio because WINE hates it.Įcho 'autospawn = no' > ~/.config/pulse/nf &

#Synergy screen wrap tv#

# when it swtches from the laptops display to the 42' TV I use for a regular # screen resizing background process that fixes the synergy screen size # I use a special script to restart synergy on the laptop as it includes a # ALL=(root) NOPASSWD: /usr/bin/killall synergyc, /home/jim/scripts/restartSynergy.sh # ALL=(root) NOPASSWD: /usr/sbin/service avahi-daemon restart, /usr/bin/killall synergys # i.e., without a password, you need the following entry in your sudoers file: # In order for the sudo commands to work in a non-interactive fashion # really just putting them into a wrapper script form because I keep forgetting I have aliases for all these functions and I'm # a shrieking laptop fan while you are trying to conentrate when it isn't even # freaks out when it can't find the server. The Synergy client running remotely must die because it Synergy must die on both machines but pulseaudio is an issue Synergy & pulseaudio must die in order for the game to # Warmachine ) which has a synergy server running on it and also a laptop that # Architectural & contextual notes: This is a desktop ( my wargamer's box called #The idea is to use this script to replace the command in the shortcut. OK there was an issue with running from the shortcut but adding a '&' at the end of the playonlinux command seems to have addressed it. I have one last concern and that is if it doesn't run from the shortcut. OK, I've rewritten it to include a polling loop. I could write it to poll for the game to see if it is running. This script handles pulseaudio and synergy quite well but the playonlinux command itself is an issue because it returns and I have to come up with a way to make my script wait. Rather than edit somebody else's script, I've written a wrapper.